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[DOI] [PMC free article] [PubMed] [Google Scholar] 246.Tian Y., Tian Q., Wu Y., Peng X., Chen Y., Li Q., Zhang G., Tian X., Ren L., Luo Z

T3 suppression on GLP-1 / GIP / glucagon agonism caloric deficit and hepatic energy expenditure together downregulate T4-to-T3 conversion

However, despite recent reports of off-label uses that have popped up in the news over the past few months, the only FDA-approved use for methylene blue is for the treatment of methemoglobinemia, a rare condition that restricts the ability of red blood cells to deliver oxygen throughout the body